Functional comparison of thymic B cells and dendritic cells in vivo.

  title={Functional comparison of thymic B cells and dendritic cells in vivo.},
  author={Petra Kleindienst and I Chr{\'e}tien and Thomas Winkler and Thomas Brocker},
  volume={95 8},
In this report we present a transgenic mouse model in which we targeted gene expression specifically to B-lymphocytes. Using the human CD19 promoter, we expressed major histocompatibility complex class II I-E molecules specifically on B cells of all tissues, but not on other cell types. If only B cells expressed I-E in a class II-deficient background, positive selection of CD4(+) T cells could not be observed. A comparison of the frequencies of I-E reactive Vbeta5(+) and Vbeta11(+) T cells… CONTINUE READING

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Inside the thymus, mLs antigen is BLOOD

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