Functional characterization of the NCC27 nuclear protein in stable transfected CHO‐K1 cells

@article{Tonini2000FunctionalCO,
  title={Functional characterization of the NCC27 nuclear protein in stable transfected CHO‐K1 cells},
  author={Raffaella Tonini and Arnaldo Ferroni and Stella M. Valenzuela and Kristina Warton and Terence J. Campbell and Samuel N. Breit and Michele Mazzanti},
  journal={The FASEB Journal},
  year={2000},
  volume={14},
  pages={1171 - 1178}
}
NCC27 belongs to a family of small, highly conserved, organellar ion channel proteins. It is constitutively expressed by native CHO‐K1 and dominantly localized to the nucleus and nuclear membrane. When CHO‐K1 cells are transfected with NCC27‐expressing constructs, synthesized proteins spill over into the cytoplasm and ion channel activity can then be detected on the plasma as well as nuclear membrane. This provided a unique opportunity to directly compare electrophysiological characteristics of… 

The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle

TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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