Functional characterization of receptors for cysteinyl-leukotrienes in sheep trachealis muscle.

@article{Jonsson1997FunctionalCO,
  title={Functional characterization of receptors for cysteinyl-leukotrienes in sheep trachealis muscle.},
  author={Eva Wikstr{\"o}m Jonsson},
  journal={Pulmonary pharmacology & therapeutics},
  year={1997},
  volume={10 1},
  pages={29-36}
}
Cysteinyl-leukotrienes (CysLTs: LTC4, LTD4 and LTE4) are inflammatory mediators which significantly contribute to the airway obstruction in asthma. At least two distinct receptor subtypes exist for cysteinyl-leukotrienes, the CysLT1- and CysLT2-receptor. The purpose of this study was to test whether sheep trachealis muscle is a useful preparation for… CONTINUE READING