Functional characterization of human variants of NFKBIA: a key regulator of immune responsiveness implicated in susceptibility to infectious and inflammatory disease

@inproceedings{Ali2010FunctionalCO,
  title={Functional characterization of human variants of NFKBIA: a key regulator of immune responsiveness implicated in susceptibility to infectious and inflammatory disease},
  author={Salman Ali and Aaron F. Hirschfeld and Rachel E. Victor and Edgardo S. Fortuno and Tobias Kollmann and Stuart E Turvey},
  year={2010}
}
Objective/purpose Genetic association studies have identified several polymorphisms in genes of the innate immunity cascade that appear to influence susceptibility to asthma and other inflammatory diseases. However, most candidate genes have not been functionally characterized for their impact on human immune responsiveness. An excellent candidate for… CONTINUE READING