Functional characterization of bacterial oligosaccharyltransferases involved in O-linked protein glycosylation.

@article{Faridmoayer2007FunctionalCO,
  title={Functional characterization of bacterial oligosaccharyltransferases involved in O-linked protein glycosylation.},
  author={Amirreza Faridmoayer and Messele A. Fentabil and D. C. Mills and J. S. Klassen and M. Feldman},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 22},
  pages={
          8088-98
        }
}
Protein glycosylation is an important posttranslational modification that occurs in all domains of life. Pilins, the structural components of type IV pili, are O glycosylated in Neisseria meningitidis, Neisseria gonorrhoeae, and some strains of Pseudomonas aeruginosa. In this work, we characterized the P. aeruginosa 1244 and N. meningitidis MC58 O glycosylation systems in Escherichia coli. In both cases, sugars are transferred en bloc by an oligosaccharyltransferase (OTase) named PglL in N… Expand
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