Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).

Abstract

Recently, a polyspecific organic cation transporter, hOCT1, was cloned from human liver. To date, limited studies examining the functional characteristics of the transporter have been performed. The purpose of the present study was to develop a mammalian expression system for hOCT1 and to characterize the interactions of various compounds with the cloned… (More)

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