Functional characterization of an insulin-responsive glucose transporter (GLUT4) from fish adipose tissue.

@article{Capilla2004FunctionalCO,
  title={Functional characterization of an insulin-responsive glucose transporter (GLUT4) from fish adipose tissue.},
  author={Encarnaci{\'o}n Capilla and M{\'o}nica D{\'i}ez D{\'i}az and Amaya Albalat and Isabel Mart{\'i}nez Navarro and Jeffrey Eugene Pessin and Konrad Keller and Josep V Planas},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2004},
  volume={287 2},
  pages={
          E348-57
        }
}
Glucose transport across the plasma membrane is mediated by a family of glucose transporter proteins (GLUTs), several of which have been identified in mammalian, avian, and, more recently, in fish species. Here, we report on the cloning of a salmon GLUT from adipose tissue with a high sequence homology to mammalian GLUT4 that has been named okGLUT4. Kinetic analysis of glucose transport following expression in Xenopus laevis oocytes demonstrated a 7.6 +/- 1.4 mM K(m) for 2-deoxyglucose (2-DG… CONTINUE READING

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