Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana

@article{Islam2006FunctionalCO,
  title={Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana},
  author={Mohammed Rafiqul Islam and Hoyeun Kim and Shin-Wook Kang and Jung Sup Kim and Young-Min Jeong and Hyun-Ju Hwang and So-Young Lee and Je-Chang Woo and Sang-Gu Kim},
  journal={Plant Molecular Biology},
  year={2006},
  volume={63},
  pages={465-477}
}
Uridine kinase (UK) and uracil phosphoribosyltransferase (UPRT) are enzymes catalyzing the formation of uridine 5′-monophosphate (UMP) from uridine and adenine 5′-triphosphate (ATP) and from uracil and phosphoribosyl-α-1-pyrophosphate (PRPP), respectively, in the pyrimidine salvage pathway. Here, we report the characterization and functional analysis of a gene AtUK/UPRT1 from Arabidopsis thaliana. Sequencing of an expressed sequence tag clone of this gene revealed that it contains a full-length… CONTINUE READING

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