Functional characterization of GM-CSF induced monocyte subsets

Abstract

Results We identified GM-CSF-dependent regulation of 402 genes, including important immune-regulatory molecules. Functional clustering of GM-CSF-regulated genes indicated induction of monocytic properties such as lymphocyte activation and tumour necrosis factor (TNF) receptor binding as well as repression of apoptosis, oxidative burst, cell motility and… (More)

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