Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells.

@article{Potta2009FunctionalCA,
  title={Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells.},
  author={Shiva Prasad Potta and Huamin Liang and Kurt Pfannkuche and Johannes Winkler and Shuhua Chen and Michael Xavier Doss and Kirsten Obernier and Naidu Kamisetti and Herbert Schulz and Norbert H{\"u}bner and J{\"u}rgen Hescheler and Agapios Sachinidis},
  journal={Hypertension},
  year={2009},
  volume={53 2},
  pages={196-204}
}
Complete transcriptome profiling of contractile smooth muscle cells (SMCs) differentiated from embryonic stem cells is crucial for the characterization of smooth muscle gene expression signatures and will contribute to defining biological and physiological processes in these cells. We have generated a transgenic embryonic stem cell line expressing both the puromycin acetyl transferase and enhanced green fluorescent protein cassettes under the control of the Acta2 promoter. Applying a specific… CONTINUE READING

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