• DOI:10.1016/S0028-3908(00)00189-1
Corpus ID: 20181576

Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel

@article{Meadows2001FunctionalCO,
  title={Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel},
  author={H. Meadows and A. Randall},
  journal={Neuropharmacology},
  year={2001},
  volume={40},
  pages={551-559}
}

H. Meadows, A. Randall

Published 2001

Chemistry, Medicine

Neuropharmacology

Human TASK-3 (hTASK-3) is a recently identified member of the two-pore domain potassium channel (2PDKC) family which in man is predominantly expressed in the cerebellum. Previous preliminary examination of this channel indicates that when expressed in Xenopus oocytes, it produces a K(+) selective background conductance and consequent shift in resting membrane potential, thus mimicking other 2PDKC. Here we describe some additional functional and pharmacological aspects of hTASK-3-mediated… CONTINUE READING

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