Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter.

Abstract

Sodium glucose cotransporters (SGLT) actively catalyse carbohydrate transport across cellular membranes. Six of the 12 known SGLT family members have the capacity to bind and/or transport monosaccharides (SGLT-1 to 6); of these, all but SGLT-5 have been characterised. Here we demonstrate that human SGLT-5 is exclusively expressed in the kidney. Four splice… (More)
DOI: 10.1016/j.febslet.2011.12.027

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