Functional assessment of the yeast Rvs161 and Rvs167 protein domains.

@article{Sivadon1997FunctionalAO,
  title={Functional assessment of the yeast Rvs161 and Rvs167 protein domains.},
  author={Pierre Sivadon and Marc Crouzet and Michel Aigle},
  journal={FEBS letters},
  year={1997},
  volume={417 1},
  pages={21-7}
}
Mutations in RVS161 and RVS167 yeast genes induce identical phenotypes associated to actin cytoskeleton disorders. The whole Rvs161 protein is similar to the amino-terminal part of Rvs167p, thus defining a RVS domain. In addition to this domain, Rvs167p contains a central glycine-proline-alanine rich domain and a SH3 domain. To assess the function of these different domains we have expressed recombinant Rvs proteins in rvs mutant strains. Phenotype analysis has shown that the RVS and SH3… CONTINUE READING

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