Functional assessment of the thyrotropin receptor-beta subunit.

Abstract

Posttranslational processing of the TSH receptor (TSHR) involves proteolysis of a single chain holoreceptor into TSHR-alpha (or A) and TSHR-beta (or B) subunits, which remain associated via disulfide bonds and which may then form oligomers. As both uncleaved and cleavage-derived forms of this receptor have been reported to bind TSH and transduce signals… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.