Functional aspects of animal microRNAs

  title={Functional aspects of animal microRNAs},
  author={A. Williams},
  journal={Cellular and Molecular Life Sciences},
  • A. Williams
  • Published 2007
  • Biology, Medicine
  • Cellular and Molecular Life Sciences
  • Abstract.MicroRNAs (miRNAs) are a recently discovered family of small regulatory molecules that function by modulating protein production. There are approximately 500 known mammalian miRNA genes, and each miRNA may regulate hundreds of different protein-coding genes. Mature miRNAs bind to target mRNAs in a protein complex known as the miRNA-induced silencing complex (miRISC), sometimes referred to as the miRNP (miRNA-containing ribonucleoprotein particles), where mRNA translation is inhibited… CONTINUE READING
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