Functional architecture of vasopressin/oxytocin receptors.

@article{Hibert1999FunctionalAO,
  title={Functional architecture of vasopressin/oxytocin receptors.},
  author={Marcel Hibert and Jan Hoflack and Susanne Trumpp-Kallmeyer and Bernard Mouillac and Bice Chini and E. Mah{\'e} and Nathalie de la Cotte and Serge Jard and Maurice Manning and Claude Barberis},
  journal={Journal of receptor and signal transduction research},
  year={1999},
  volume={19 1-4},
  pages={
          589-96
        }
}
Three-dimensional models of G protein-coupled receptors (GPCR) have been defined using most experimental data available and protein modeling techniques. The endogenous ligand binding sites have been qualitatively described and putative receptor activation mechanisms have been proposed. The model has been recently refined to take into account recent crystallographic data. Most experimental results published are in excellent qualitative agreement with the initial model. We have undertaken to… CONTINUE READING

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