Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila

@inproceedings{Saumweber2018FunctionalAO,
  title={Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila},
  author={Timo Saumweber and Astrid Rohwedder and Michael Schleyer and Katharina Eichler and Yi-chun Chen and Yoshinori Aso and Albert Cardona and Claire Eschbach and Oliver Kobler and Anne Kirsti Kittilsen Voigt and Archana Durairaja and Nino Mancini and Marta Zlatic and James W. Truman and Andreas S. Thum and Bertram Gerber},
  booktitle={Nature Communications},
  year={2018}
}
The brain adaptively integrates present sensory input, past experience, and options for future action. The insect mushroom body exemplifies how a central brain structure brings about such integration. Here we use a combination of systematic single-cell labeling, connectomics, transgenic silencing, and activation experiments to study the mushroom body at single-cell resolution, focusing on the behavioral architecture of its input and output neurons (MBINs and MBONs), and of the mushroom body… CONTINUE READING
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