Functional architecture of cortex revealed by optical imaging of intrinsic signals

@article{Grinvald1986FunctionalAO,
  title={Functional architecture of cortex revealed by optical imaging of intrinsic signals},
  author={Amiram Grinvald and Edmund E. Lieke and Ron D. Frostig and Charles D. Gilbert and Torsten N. Wiesel},
  journal={Nature},
  year={1986},
  volume={324},
  pages={361-364}
}
  • Amiram Grinvald, Edmund E. Lieke, +2 authors Torsten N. Wiesel
  • Published 1986
  • Materials Science, Medicine
  • Nature
  • Optical imaging of cortical activity offers several advantages over conventional electrophysiological and anatomical techniques. One can map a relatively large region, obtain successive maps to different stimuli in the same cortical area and follow variations in response over time. In the intact mammalian brain this imaging has been accomplished with the aid of voltage sensitive dyes1–5. However, it has been known for many years that some intrinsic changes in the optical properties of the… CONTINUE READING

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