Functional architecture of basal ganglia circuits: neural substrates of parallel processing
@article{Alexander1990FunctionalAO, title={Functional architecture of basal ganglia circuits: neural substrates of parallel processing}, author={G. E. Alexander and M. Crutcher}, journal={Trends in Neurosciences}, year={1990}, volume={13}, pages={266-271} }
Concepts of basal ganglia organization have changed markedly over the past decade, due to significant advances in our understanding of the anatomy, physiology and pharmacology of these structures. Independent evidence from each of these fields has reinforced a growing perception that the functional architecture of the basal ganglia is essentially parallel in nature, regardless of the perspective from which these structures are viewed. This represents a significant departure from earlier… CONTINUE READING
Figures and Topics from this paper
Figures
Paper Mentions
Interventional Clinical Trial
Background:
- Deep brain stimulation (DBS) is an approved surgery for certain movement disorders, like
Parkinson's disease, that do not respond well to other treatments. DBS uses… Expand
Conditions | Dystonia, Essential Tremor, Parkinson's Disease |
---|---|
Intervention | Procedure |
Observational Clinical Trial
Bipolar disorder is a complex psychiatric disorder characterized by recurrent episodes of
mania or hypomania and depression, and affects around one to three percent of the population… Expand
Conditions | Brain Voxel-based Morphometry in Mania |
---|---|
Intervention | Diagnostic Test |
Observational Clinical Trial
Objective
The objective of this pilot study is to characterize the abnormal neuronal firing patterns of
basal ganglia neurons and those in the premotor cortex in patients with… Expand
Conditions | Obsessive-Complusive Disorder |
---|
Observational Clinical Trial
This study will examine how the brain controls speech in patients with spasmodic dysphonia, a
voice disorder that involves involuntary spasms of muscles in the larynx (voice box… Expand
Conditions | Focal Dystonia, Spasmodic Dysphonia |
---|
3,778 Citations
Functional Architecture of the Rodent Substantia Nigra Pars Reticulata: Evidence for Segregated Channels
- Biology
- 1994
- 13
Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop
- Biology, Medicine
- Brain Research Reviews
- 1995
- 1,823
Functional anatomy of the basal ganglia
- Psychology, Medicine
- Movement disorders : official journal of the Movement Disorder Society
- 2002
- 849
The modular organization of brain systems. Basal forebrain: the last frontier.
- Biology, Medicine
- Progress in brain research
- 2002
- 127
Anatomical Relationships Between the Prefrontal Cortex and the Basal Ganglia in the Rat
- Biology
- 1994
- 88
The basal ganglia: anatomy, physiology, and pharmacology.
- Medicine, Psychology
- The Psychiatric clinics of North America
- 2004
- 88
The primate basal ganglia: parallel and integrative networks
- Psychology, Medicine
- Journal of Chemical Neuroanatomy
- 2003
- 1,235
- PDF
References
SHOWING 1-10 OF 93 REFERENCES
Parallel organization of functionally segregated circuits linking basal ganglia and cortex.
- Biology, Medicine
- Annual review of neuroscience
- 1986
- 7,568
- PDF
The functional anatomy of basal ganglia disorders
- Psychology, Medicine
- Trends in Neurosciences
- 1989
- 4,707
- PDF
A proposed conceptual reorganization of the basal ganglia and telencephalon
- Biology, Medicine
- Neuroscience
- 1979
- 126
Sagittal cytoarchitectonic maps of the Macaca mulatta thalamus with a revised nomenclature of the motor‐related nuclei validated by observations on their connectivity
- Biology, Medicine
- The Journal of comparative neurology
- 1987
- 211
Bilateral projections from precentral motor cortex to the putamen and other parts of the basal ganglia. An autoradiographic study inMacaca fascicularis
- Biology, Medicine
- Brain Research
- 1975
- 743
The origin of thalamic inputs to the arcuate premotor and supplementary motor areas
- Biology, Medicine
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- 1984
- 761
- PDF
Longitudinal topography and interdigitation of corticostriatal projections in the rhesus monkey
- Biology, Medicine
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- 1985
- 1,057
- PDF
Distribution of cerebellar terminations and their relation to other afferent terminations in the ventral lateral thalamic region of the monkey
- Biology, Medicine
- Brain Research Reviews
- 1983
- 588
Projection of the digit and wrist area of precentral gyrus to the putamen: Relation between topography and physiological properties of neurons in the putamen
- Psychology, Medicine
- Brain Research
- 1985
- 152
Anatomical analysis of ventrolateral thalamic input to primate motor cortex.
- Psychology, Medicine
- Journal of neurophysiology
- 1976
- 250