Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension.

@article{RodriguezPorcel2006FunctionalAS,
  title={Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension.},
  author={Martin Rodriguez-Porcel and Xiang-yang Zhu and Alejandro R. Chade and Beatriz Amores-Arriaga and Noel M. Caplice and Erik L. Ritman and Amir Lerman and Lilach Orly Lerman},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={290 3},
  pages={H978-84}
}
Advanced hypertension (HT), associated with left ventricular hypertrophy (LVH), impairs myocardial microvascular function and structure and leads to increased myocardial hypoxia and growth factor activation. However, the effect of HT on microvascular architecture and its relation to microvascular function, before the development of LVH (early HT), remains unclear. By way of method, pigs were studied after 12 wk of renovascular HT (n = 7) or control (n = 7) animals. Myocardial microvascular… CONTINUE READING
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