Functional and structural rat kidney changes caused by peroral or parenteral lithium treatment.

@article{Plenge1981FunctionalAS,
  title={Functional and structural rat kidney changes caused by peroral or parenteral lithium treatment.},
  author={Per Plenge and Erling Mellerup and Tove N\orgaard},
  journal={Acta psychiatrica Scandinavica},
  year={1981},
  volume={63 4},
  pages={303-13}
}
Renal functional and structural changes were studied in rats treated with lithium for 5 months. The lithium was administered in two different ways: in the food or as a daily intraperitoneal injection. In the perorally treated rats serum lithium was relatively constant during the day. In the injected rats serum lithium reached a high peak value just after the injection followed by a decrease to very low values. In all rats an increased water consumption and a reduced renal concentration ability… CONTINUE READING

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