Functional and structural integrity of porcine pancreatic grafts subjected to a period of warm ischemia and cold preservation with histidine-tryptophan-ketoglutarate (custodiol) or University of Wisconsin solution.

@article{Troisi2003FunctionalAS,
  title={Functional and structural integrity of porcine pancreatic grafts subjected to a period of warm ischemia and cold preservation with histidine-tryptophan-ketoglutarate (custodiol) or University of Wisconsin solution.},
  author={R I Troisi and Daniel J Meester and Carolien Van Den Broecke and Claude A. Cuvelier and Tom Fiers and Bernard de Hemptinne and Uwe J Hesse},
  journal={Transplantation},
  year={2003},
  volume={75 11},
  pages={1793-9}
}
BACKGROUND University of Wisconsin (UW) solution (Viaspan) is currently used to preserve organs from nonheartbeating donors. Histidine-tryptophan-ketoglutarate (HTK) solution (Custodiol) is of proven efficacy in experimental pancreas preservation, but its efficacy in combined warm ischemia (WI) and cold ischemia (CI) is unknown. The viability of HTK-preserved porcine pancreatic grafts was assessed after various periods of WI and compared with grafts flushed and preserved with UW solution… CONTINUE READING
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