Functional and structural aspects of the Kell blood group system.

@article{Lee2000FunctionalAS,
  title={Functional and structural aspects of the Kell blood group system.},
  author={Soohee Lee and David Russo and Colvin M. Redman},
  journal={Transfusion medicine reviews},
  year={2000},
  volume={14 2},
  pages={93-103}
}
Two covalently linked proteins, Kell and XK, constitute the Kell blood group system. Kell, a 93-Kd type II glycoprotein, is highly polymorphic and carries all but 1 of the known Kell antigens, and XK, which traverses the membrane 10 times, carries a single antigen, the ubiquitous Kx. The Kell/XK complex is not limited to erythroid tissues and may have multiple physiological roles. Absence of one of the component proteins, XK, is associated with abnormal red cell morphology and late-onset forms… CONTINUE READING