Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.

Abstract

OBJECTIVE To address the functional and prognostic relevance of the -173 single-nucleotide G-to-C polymorphism of the macrophage migration inhibitory factor (MIF) gene in patients with systemic-onset juvenile idiopathic arthritis (systemic-onset JIA) by evaluating its association with serum and synovial fluid levels of MIF, with glucocorticoid requirement… (More)

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@article{benedetti2003FunctionalAP, title={Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.}, author={F De benedetti and Cristina Meazza and Marina S. Vivarelli and Federica Rossi and Angela Pistorio and Rebecca S. Lamb and Mark Lunt and Wendy Thomson and Angelo Ravelli and Rachelle P. Donn and Alberto Martini}, journal={Arthritis and rheumatism}, year={2003}, volume={48 5}, pages={1398-407} }