Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

@article{Stein1993FunctionalAP,
  title={Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.},
  author={Bernd Stein and Patricia C. Cogswell and Albert S Baldwin},
  journal={Molecular and cellular biology},
  year={1993},
  volume={13 7},
  pages={3964-74}
}
NF-kappa B and C/EBP represent distinct families of transcription factors that target unique DNA enhancer elements. The heterodimeric NF-kappa B complex is composed of two subunits, a 50- and a 65-kDa protein. All members of the NF-kappa B family, including the product of the proto-oncogene c-rel, are characterized by their highly homologous approximately 300-amino-acid N-terminal region. This Rel homology domain mediates DNA binding, dimerization, and nuclear targeting of these proteins. C/EBP… CONTINUE READING
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