Functional and molecular identification of 5-hydroxytryptamine receptors in rabbit pulmonary artery: involvement in complex regulation of noradrenaline release.

Abstract

The rabbit pulmonary artery was used to examine whether presynaptic serotonin (5-HT) receptors modulate noradrenaline (NA) release also in this blood vessel and to confirm their presence with molecular biology techniques. Arteries preincubated with [3H]NA were superfused in the presence of the alpha2-adrenoceptor blocker rauwolscine and the effects of 5-HT… (More)

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