Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy

@inproceedings{Panaite2013FunctionalAH,
  title={Functional and histopathological identification of the respiratory failure in a DMSXL transgenic mouse model of myotonic dystrophy},
  author={Petrica-Adrian Panaite and Thierry Kuntzer and Genevi{\`e}ve Gourdon and Johannes Alexander Lobrinus and Ibtissam Barakat-Walter},
  booktitle={Disease models & mechanisms},
  year={2013}
}
Acute and chronic respiratory failure is one of the major and potentially life-threatening features in individuals with myotonic dystrophy type 1 (DM1). Despite several clinical demonstrations showing respiratory problems in DM1 patients, the mechanisms are still not completely understood. This study was designed to investigate whether the DMSXL transgenic mouse model for DM1 exhibits respiratory disorders and, if so, to identify the pathological changes underlying these respiratory problems… CONTINUE READING