Functional and expression analyses of the cop operon, required for copper resistance in Agrobacterium tumefaciens.

@article{Nawapan2009FunctionalAE,
  title={Functional and expression analyses of the cop operon, required for copper resistance in Agrobacterium tumefaciens.},
  author={Sirikan Nawapan and Nisanart Charoenlap and Anchalee Charoenwuttitam and Panatda Saenkham and Skorn Mongkolsuk and Paiboon Vattanaviboon},
  journal={Journal of bacteriology},
  year={2009},
  volume={191 16},
  pages={5159-68}
}
The copper resistance determinant copARZ, which encodes a CPx-type copper ATPase efflux protein, a transcriptional regulator, and a putative intracellular copper chaperone, was functionally characterized for the phytopathogenic bacterium Agrobacterium tumefaciens. These genes are transcribed as an operon, and their expression is induced in response to increasing copper and silver ion concentrations in a copR-dependent fashion. Analysis of the copARZ promoter revealed a putative CopR binding box… CONTINUE READING

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