Functional and defective components of avian endogenous virus long terminal repeat enhancer sequences.

@article{Habel1993FunctionalAD,
  title={Functional and defective components of avian endogenous virus long terminal repeat enhancer sequences.},
  author={D E Habel and K L Dohrer and Kathleen F. Conklin},
  journal={Journal of virology},
  year={1993},
  volume={67 3},
  pages={1545-54}
}
Oncogenic avian retroviruses, such as Rous sarcoma virus (RSV) and the avian leukosis viruses, contain a strong enhancer in the U3 portion of the proviral long terminal repeat (LTR). The LTRs of a second class of avian retroviruses, the endogenous viruses (ev) lack detectable enhancer activity. By creating ev-RSV hybrid LTRs, we previously demonstrated that… CONTINUE READING