Functional and clinical relevance of chondroitin sulfate proteoglycan 4.

  title={Functional and clinical relevance of chondroitin sulfate proteoglycan 4.},
  author={Michael Campoli and Soldano Ferrone and Xinhui Wang},
  journal={Advances in cancer research},
The lack of effective conventional therapies for the treatment of advanced stage melanoma has stimulated interest in the development of novel strategies for the management of patients with malignant melanoma. Among them, immunotherapy has attracted much attention because of the potential role played by immunological events in the clinical course of melanoma. For many years, T cell-based immunotherapy has been emphasized in part because of the disappointing results of the monoclonal antibody… CONTINUE READING


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