Functional and biophysical characterization of recombinant human hepatocyte growth factor isoforms produced in Escherichia coli.

@article{Stahl1997FunctionalAB,
  title={Functional and biophysical characterization of recombinant human hepatocyte growth factor isoforms produced in Escherichia coli.},
  author={Stefanie Stahl and Paul T Wingfield and Joshua D. Kaufman and Lewis K. Pannell and Vittoria Cioce and Hiromi Sakata and William G. Taylor and Jeffrey S. Rubin and Donald P Bottaro},
  journal={The Biochemical journal},
  year={1997},
  volume={326 ( Pt 3)},
  pages={763-72}
}
Hepatocyte growth factor (HGF) is a pluripotent secreted protein that stimulates a wide array of cellular targets, including hepatocytes and other epithelial cells, melanocytes, endothelial and haematopoietic cells. Multiple mRNA species transcribed from a single HGF gene encode at least three distinct proteins: the full-length HGF protein and two truncated HGF isoforms that encompass the N-terminal (N) domain through kringle 1 (NK1) or through kringle 2 (NK2). We report the high-level… CONTINUE READING
20 Citations
2 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-2 of 2 references

Mechanisms of Protein Folding (Pain, R

  • R. Christensen, R. H. Pain
  • 1994

Hepatocyte Growth Factor-Scatter Factor

  • G. A. Rodrigues, M. Park
  • 1993

Similar Papers

Loading similar papers…