Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery.

@article{Zimmermann2003FunctionalAB,
  title={Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery.},
  author={Norbert Zimmermann and Angela Wenk and Untae Kim and P Kienzle and A A Weber and Emmeran Gams and Karsten Schroer and Thomas Hohlfeld},
  journal={Circulation},
  year={2003},
  volume={108 5},
  pages={542-7}
}
BACKGROUND Aspirin inhibits platelet activation and reduces atherothrombotic complications in patients at risk of myocardial infarction and stroke. However, a sufficient inhibition of platelet function by aspirin is not always achieved. The causes of this aspirin resistance are unknown. METHODS AND RESULTS Patients undergoing coronary artery bypass grafting (CABG) have a high incidence of aspirin resistance. To evaluate functional and biochemical responses to aspirin, platelet-rich plasma was… CONTINUE READING