Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction

@inproceedings{Li2009FunctionalAT,
  title={Functional and Transcriptional Characterization of Human Embryonic Stem Cell-Derived Endothelial Cells for Treatment of Myocardial Infarction},
  author={Zongjin Li and Kitchener D. Wilson and Bryan Smith and Daniel L. Kraft and Fangjun Jia and Mei Huang and Xiao-Yan Xie and Robert Clayton Robbins and Sanjiv Sam Gambhir and Irving L Weissman and Joseph C Wu},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Differentiation of human embryonic stem cells into endothelial cells (hESC-ECs) has the potential to provide an unlimited source of cells for novel transplantation therapies of ischemic diseases by supporting angiogenesis and vasculogenesis. However, the endothelial differentiation efficiency of the conventional embryoid body (EB) method is low while the 2-dimensional method of co-culturing with mouse embryonic fibroblasts (MEFs) require animal product, both of which can limit the… CONTINUE READING
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