Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature

@inproceedings{Nicola2015FunctionalAS,
  title={Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature},
  author={Maura Di Nicola and Giulio Barteselli and Laura Dell'arti and Roberto Ratiglia and Francesco Viola},
  booktitle={BioMed research international},
  year={2015}
}
Deferoxamine mesylate (DFO) is the most commonly used iron-chelating agent to treat transfusion-related hemosiderosis. Despite the clear advantages for the use of DFO, numerous DFO-related systemic toxicities have been reported in the literature, as well as sight-threatening ocular toxicity involving the retinal pigment epithelium (RPE). The damage to the RPE can lead to visual field defects, color-vision defects, abnormal electrophysiological tests, and permanent visual deterioration. The… CONTINUE READING
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