Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma

@inproceedings{Thompson2017FunctionalAH,
  title={Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma},
  author={Heather L. Thompson and Megan J Smithey and Charles D. Surh and Janko Nikolich-Žugich},
  booktitle={Front. Immunol.},
  year={2017}
}
Adults over 65 years of age are more vulnerable to infectious disease and show poor responses to vaccination relative to those under 50. A complex set of age-related changes in the immune system is believed to be largely responsible for these defects. These changes, collectively termed immune senescence, encompass alterations in both the innate and adaptive immune systems, in the microenvironments where immune cells develop or reside, and in soluble factors that guide immune homeostasis and… CONTINUE READING
6
Twitter Mentions

References

Publications referenced by this paper.
SHOWING 1-10 OF 74 REFERENCES

lymphoid tissue microarchitecture in antimicrobial immune defence

T Junt, E Scandella, function Ludewig B. Form follows
  • Nat Rev Immunol
  • 2008
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL