Functional analysis of yersiniabactin transport genes of Yersinia enterocolitica.

  title={Functional analysis of yersiniabactin transport genes of Yersinia enterocolitica.},
  author={Daniela Brem and Cosima Pelludat and Alexander Rakin and Christoph A Jacobi and Juergen Heesemann},
  volume={147 Pt 5},
Yersinia enterocolitica O:8, biogroup (BG) IB, strain WA-C carries a high-pathogenicity island (HPI) including iron-repressible genes (irp1-9, fyuA) for biosynthesis and uptake of the siderophore yersiniabactin (Ybt). The authors report the functional analysis of irp6,7,8, which show 98-99% similarity to the corresponding genes ybtP,Q,X on the HPI of Yersinia pestis. It was demonstrated that irp6,7 are involved in ferric (Fe)-Ybt utilization and mouse virulence of Y. enterocolitica, thus… CONTINUE READING

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