Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.

@article{Teisanu2011FunctionalAO,
  title={Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.},
  author={Roxana M Teisanu and Huaiyong Chen and Keitaro Matsumoto and Jonathan L. McQualter and Erin N. Potts and William Michael Foster and Ivan Bertoncello and Barry R Stripp},
  journal={American journal of respiratory cell and molecular biology},
  year={2011},
  volume={44 6},
  pages={794-803}
}
Air spaces of the mammalian lung are lined by a specialized epithelium that is maintained by endogenous progenitor cells. Within bronchioles, the abundance and distribution of progenitor cells that contribute to epithelial homeostasis change as a function of maintenance versus repair. It is unclear whether functionally distinct progenitor pools or a single progenitor cell type maintain the epithelium and how the behavior is regulated in normal or disease states. To address these questions, we… CONTINUE READING
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