Functional analysis of the white gene of Drosophila by P-factor-mediated transformation.

  title={Functional analysis of the white gene of Drosophila by P-factor-mediated transformation.},
  author={W. J. Gehring and Roman Klemenz and Ursula Weber and Urs Kloter},
  journal={The EMBO journal},
  volume={3 9},
A 12-kb DNA segment spanning the white (w) locus of Drosophila has been inserted into a P-transposon vector and used for P-factor-mediated germ-line transformation. Several red-eyed transformants were recovered which complement the white mutant phenotype. Analysis of the eye pigments and the interaction with the zeste mutation indicates that the w gene inserted at several new chromosomal sites is expressed normally. The tissue-specific accumulation of w transcripts, as studied by in situ… CONTINUE READING

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