Functional analysis of the aquaporin gene family in Caenorhabditis elegans.

@article{Huang2007FunctionalAO,
  title={Functional analysis of the aquaporin gene family in Caenorhabditis elegans.},
  author={Chunyi George Huang and Todd Lamitina and Peter Agre and Kevin Strange},
  journal={American journal of physiology. Cell physiology},
  year={2007},
  volume={292 5},
  pages={C1867-73}
}
Aquaporin channels facilitate the transport of water, glycerol, and other small solutes across cell membranes. The physiological roles of many aquaporins remain unclear. To better understand aquaporin function, we characterized the aquaporin gene family in the nematode Caenorhabditis elegans. Eight canonical aquaporin-encoding genes (aqp) are present in the worm genome. Expression of aqp-2, aqp-3, aqp-4, aqp-6, or aqp-7 in Xenopus oocytes increased water permeability five- to sevenfold… CONTINUE READING