Functional analysis of the NUP98-CCDC28A fusion protein.

Abstract

BACKGROUND The nucleoporin gene NUP98 is rearranged in more than 27 chromosomal abnormalities observed in childhood and adult, de novo and therapy-related acute leukemias of myeloid and T-lymphoid origins, resulting in the creation of fusion genes and the expression of chimeric proteins. We report here the functional analysis of the NUP98-coiled-coil domain… (More)
DOI: 10.3324/haematol.2011.047969

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