Functional analysis of the N-terminal domain of Tat protein of the human immunodeficiency virus type 1.

Abstract

The Tat protein of human immunodeficiency virus type 1 (HIV-1) is a potent trans-activator of the viral long terminal repeat (LTR). The N-terminal region of Tat is rich in proline and acidic residues analogous to the activation domains of other transcription factors such as GAL-4 and CTF/NF-1. Several basic residues are also present in this region. To… (More)

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Cite this paper

@article{Reddy1992FunctionalAO, title={Functional analysis of the N-terminal domain of Tat protein of the human immunodeficiency virus type 1.}, author={M V Reddy and M. Desai and J I Jeyapaul and Dheerendra Prasad and T Seshamma and Denise Palmeri and S. A. Khan}, journal={Oncogene}, year={1992}, volume={7 9}, pages={1743-8} }