Functional analysis of pattern recognition receptors in miniature dachshunds with inflammatory colorectal polyps

@inproceedings{Igarashi2015FunctionalAO,
  title={Functional analysis of pattern recognition receptors in miniature dachshunds
with inflammatory colorectal polyps},
  author={Hirotaka Igarashi and Koichi Ohno and Aki Fujiwara-Igarashi and Hideyuki Kanemoto and Kenjiro Fukushima and Yuko Goto-Koshino and Kazuyuki Uchida and Hajime Tsujimoto},
  booktitle={The Journal of veterinary medical science},
  year={2015}
}
Inflammatory colorectal polyps (ICRPs) frequently occur in miniature dachshunds (MDs) in Japan. MDs with ICRPs develop multiple polyps with severe neutrophil infiltration that respond to immunosuppressive therapy. Therefore, ICRPs are thought to constitute a novel, breed-specific form of canine inflammatory bowel disease (IBD). Pattern recognition receptors (PRRs) play a key role in the distinction of pathogens from commensal bacteria and food antigens. Dysfunction resulting from genetic… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 51 references

Chronic stimulation of Nod2 mediates tolerance to bacterial products.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 8 Excerpts
Highly Influenced

International IBD Genetics Consortium (IIBDGC)

L. Jostins, S. Ripke, +103 authors H ChoJ.
2012
View 9 Excerpts
Highly Influenced

Inflammatory bowel disease in the dog: differences and similarities with humans.

World journal of gastroenterology • 2010
View 9 Excerpts
Highly Influenced

Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics

S. de Kivit, M. C. Tobin, C. B. Forsyth, A. Keshavarzian, A. L. Landay
Front. Immunol • 2014
View 1 Excerpt

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