Functional analysis of human replication protein A in nucleotide excision repair.

@article{Stigger1998FunctionalAO,
  title={Functional analysis of human replication protein A in nucleotide excision repair.},
  author={E Stigger and Rachid Drissi and Sang H Lee},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 15},
  pages={9337-43}
}
Human replication protein A (RPA) is a three-subunit protein complex (70-, 34-, and 11-kDa subunits) involved in DNA replication, repair, and recombination. Both the 70- (p70) and 34-kDa (p34) subunits interact with Xeroderma pigmentosum group A complementing protein (XPA), a key protein involved in nucleotide excision repair. Our deletion analysis indicated that no particular domain(s) of RPA p70 was essential for its interaction with XPA, whereas 33 amino acids from the C terminus of p34… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Lack of EGF receptor contributes to drug sensitivity of human germline cells

British Journal of Cancer • 2005
View 1 Excerpt
Highly Influenced

Molecular interaction map of the mammalian cell cycle control and DNA repair systems.

Molecular biology of the cell • 1999
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…