Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis

@article{Julsing2007FunctionalAO,
  title={Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis},
  author={Mattijs Kamiel Julsing and Michael Rijpkema and Herman J. Woerdenbag and Wim J Quax and Oliver Kayser},
  journal={Applied Microbiology and Biotechnology},
  year={2007},
  volume={75},
  pages={1377 - 1384}
}
In comparison to other bacteria Bacillus subtilis emits the volatile compound isoprene in high concentrations. Isoprene is the smallest representative of the natural product group of terpenoids. A search in the genome of B. subtilis resulted in a set of genes with yet unknown function, but putatively involved in the methylerythritol phosphate (MEP) pathway to isoprene. Further identification of these genes would give the possibility to engineer B. subtilis as a host cell for the production of… CONTINUE READING

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