Functional analysis of cystathionine gamma-synthase in genetically engineered potato plants.

@article{Kreft2003FunctionalAO,
  title={Functional analysis of cystathionine gamma-synthase in genetically engineered potato plants.},
  author={Oliver Kreft and Rainer Hoefgen and Holger Hesse},
  journal={Plant physiology},
  year={2003},
  volume={131 4},
  pages={
          1843-54
        }
}
In plants, metabolic pathways leading to methionine (Met) and threonine diverge at the level of their common substrate, O-phosphohomoserine (OPHS). To investigate the regulation of this branch point, we engineered transgenic potato (Solanum tuberosum) plants affected in cystathionine gamma-synthase (CgS), the enzyme utilizing OPHS for the Met pathway. Plants overexpressing potato CgS exhibited either: (a) high transgene RNA levels and 2.7-fold elevated CgS activities but unchanged soluble Met… CONTINUE READING

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