Functional analysis of an archaebacterial voltage-dependent K+ channel

@article{Ruta2003FunctionalAO,
  title={Functional analysis of an archaebacterial voltage-dependent K+ channel},
  author={Vanessa Ruta and Youxing Jiang and Alice Lee and Jiayun Chen and Roderick MacKinnon},
  journal={Nature},
  year={2003},
  volume={422},
  pages={180-185}
}
All living organisms use ion channels to regulate the transport of ions across cellular membranes. Certain ion channels are classed as voltage-dependent because they have a voltage-sensing structure that induces their pores to open in response to changes in the cell membrane voltage. Until recently, the voltage-dependent K+, Ca2+ and Na+ channels were regarded as a unique development of eukaryotic cells, adapted to accomplish specialized electrical signalling, as exemplified in neurons. Here we… CONTINUE READING

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