Functional analysis of a crustacean microRNA in host-virus interactions.

  title={Functional analysis of a crustacean microRNA in host-virus interactions.},
  author={Tianzhi Huang and Xiaobo Zhang},
  journal={Journal of virology},
  volume={86 23},
Growing evidence from mammals suggests that host microRNAs (miRNAs) play important roles in the antiviral immune response. However, the roles of invertebrate miRNAs in response to virus infection remain to be investigated. Based on our previous studies, the shrimp miR-7 was found to be upregulated in response to white spot syndrome virus (WSSV) infection. In this study, the results showed that shrimp miR-7 could target the 3'-untranslated region (3'UTR) of the WSSV early gene wsv477, implying… CONTINUE READING