Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.

@article{Bailey2010FunctionalAO,
  title={Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence.},
  author={Dalan Bailey and Ioannis Karakasiliotis and Surender Vashist and Liliane Man Wah Chung and Jivan Rees and Nora McFadden and Alicia Benson and Felix O. Yarovinsky and Peter Simmonds and Ian Goodfellow},
  journal={Journal of virology},
  year={2010},
  volume={84 6},
  pages={2859-70}
}
Interactions of host cell factors with RNA sequences and structures in the genomes of positive-strand RNA viruses play various roles in the life cycles of these viruses. Our understanding of the functional RNA elements present in norovirus genomes to date has been limited largely to in vitro analysis. However, we recently used reverse genetics to identify evolutionarily conserved RNA structures and sequences required for norovirus replication. We have now undertaken a more detailed analysis of… CONTINUE READING
10 Citations
47 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Attenuated VOL

  • M. Rodriguez Pulido, F. Sobrino, B. Borrego, M. Saiz
  • J. Virol
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…