Functional analysis in type Ia group B Streptococcus of a cluster of genes involved in extracellular polysaccharide production by diverse species of streptococci.

@article{Cieslewicz2001FunctionalAI,
  title={Functional analysis in type Ia group B Streptococcus of a cluster of genes involved in extracellular polysaccharide production by diverse species of streptococci.},
  author={Michael J Cieslewicz and Dennis L Kasper and Yanzhuang Wang and Michael R. Wessels},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 1},
  pages={139-46}
}
Several species of streptococci produce extracellular polysaccharides in the form of secreted exopolysaccharides or cell-associated capsules. Although the biological properties and repeating unit structures of these polysaccharides are diverse, sequence analysis of the genes required for their production has revealed a surprising degree of conservation among five genes found in the capsule gene cluster of each of several polysaccharide-producing streptococci. To determine the function of these… CONTINUE READING

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