Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts.

@article{Nomoto1997FunctionalAO,
  title={Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts.},
  author={Shuji Nomoto and Yuichiro Watanabe and Jun Ninomiya-Tsuji and Li Xi Yang and Yoshiyuki Nagai and Kazutoshi Kiuchi and Masatoshi Hagiwara and Hidetoshi Hidaka and Kenji Matsumoto and Kenji Irie},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={1997},
  volume={2 10},
  pages={601-14}
}
BACKGROUND The PKC1 gene of Saccharomyces cerevisiae encodes a homologue of mammalian protein kinase C (PKC) that is required for yeast cell growth. Pkc1 has been proposed to regulate a protein kinase cascade which includes the Bck1, Mkk1/Mkk2 and Mpk1 kinases. The functional relationship between Pkc1 and mammalian PKCs is unknown. Another signal… CONTINUE READING